Endocrine Abstracts

The present study was undertaken to determine morphological and biochemical characteristics of GH-producing tumor. We collected consecutively 15 patients with acromegaly, and they were 6 males and 9 females with the ages of 58.5±9.9 years. As for tumor size, 7 patients had macroadenoma, 5 had microadenoma and three had empty sella with some atypical expansions. Only 3 patients had intrasellar tumor and 2 patients had empty sella in MRI finding. Other 10 patients had atypi...

Background and aims: Excess GH causes insulin resistance resulting in impaired glucose metabolism. Although diabetes mellitus (DM) is common in patients with acromegaly, diabetic ketoacidosis (DKA) is rarely associated with acromegaly. Actually only 11 DKA patients have been anecdotally reported as the first presentation of acromegaly so far. Here we present nine cases of DKA as the first presentation of 860 consecutive patients with acromegaly and their clinical characteristi...